$MS0107$CL$LL3600$PL.12$SL.13$STc2$SZ.29Sy$PH$PH$PHn$UMopsis$ENo$UMf$ENSi$PH$PH$PHx$ENA$PH$PH$PH$PHr$PH$PHt$PH$PHi$UMcl$UMes$US$CC
$US$FL
$PPon$END$PHr$PH$PH$PH$PHu$PHg$UM$UMs$CC
$FL
$PP$PP$PP$SZ19$ST4by$ENA$PH$PH$PHl$UMeis$UMt$PH$PHer$ENCro$UMwl$UMe$PHy$CC
$AF020$CC
$MS0208$STc1$SZ14I.$ENG$PHener$PHa$PHl$ENSu$PHr$PH$PHv$UMe$PHy$SZ13$FL
$MS0600$AF009$RC0030$STa3A.$EN$PH$PH$PH$PH$PH$PH$PH$RCAlmost universal ignorance of the true facts about Drugs.  Wild statements on both sides;
delights and dangers exaggerated.$US$FL
$PP$PP$RC0030B.$EN$FS$UM$UM$RCGeneral account of the principal drugs which have a psychical interest:$ENAlcohol, Ether,
Chloroform, Hashish, Anhalonium Lewinii,* Opium (various forms), Atropine$FJ
(Belladonna),$SSi $SXStramonium,$SSo $SXOpium derivatives:$ENCocaine,$ST4$SSi$ST3 $SXMorphine, Heroin.$US$FL
$PP$PP$RC0030C.$EN$FS$UM$RCTwo main types of drug:$EN``One man's meat is another man's poison.''$US$FL
$PP$PP$RC0030D.$EN$PH$PH$PH$PH$PH$RCNeed to distinguish between the various forms of intoxication, and to identify the true
cause of the action of any given drug.$US$FL
$PP$PP$RC0030E.$EN$FS$UM$UM$UM$UM$RCThe general use of each drug, and the reason in each case of any tendency to abuse. The
action of a certain drug upon a certain person in good health totally different to that upon a
sick one.$US$FL
$FL
$MS0201$STc1$SZ14II.$ENHist$PHor$PHic$PH$PHal$ENSu$PHr$PH$PHv$UMe$PHy$SZ13$FL
$MS0600$AF009$RC0030$STa3A.$EN$PH$PH$PH$PH$PH$PH$PH$RCEthnographical and climatic distribution.$US$FL
$PP$PP$RC0030B.$EN$FS$UM$UM$RCConnection of intoxication, mania, and religious ecstasy.  Ceremonious use of drugs by
various cults.$US$FL
$PP$PP$RC0030C.$EN$FS$UM$RCMy own researches since 1899.  Why I took up the study.  The personal equation.
Summary of my results.  Importance of the technique of administration.  Experiments on
other people.$FL
$LU$IX$FL
$SZ10$PL.09*$FSThe peyote cactus, $ST4Lophophora williamsii$ST3 in modern taxonomy.  Crowley refers to the Parke, Davis & Co. liquid
preparation, in which the chief alkaloid mescaline was more concentrated than in mescal buttons.  R.E. Schultes and
A. Hofmann, $ST4The Botany and Chemistry of Hallucinogens$ST3, (Springfield, Ill: Thomas, 1973), p.$FS132.$FL
$PP$PP$SSi$FS$SXAtropine is not now considered a natural component of $ST4Atropa belladonna$ST3, but rather a byproduct of chemical or
heat extraction during which the chief alkaloid hyoscyamine partly changes to atropine.  Neither alkaloid is reported
to be hallucinogenic in non-toxic quantities, unlike scopolamine, another alkaloid present in smaller amounts.  $ST4Ibid$ST3,
p.$FS161.$FL
$PP$PP$SSo$FS$ST4$SXStramonium$ST3 is one of four divisions of the genus $ST4Datura$ST3, and has three species.  Crowley probably refers to thorn
apple, also called jimson weed, whose principal active component is scopolamine.  $ST4Ibid$ST3, p.$FS167.$FL
$PP$PP$ST4$SSi$ST3$FS$SXProbably codeine in this context.  We let cocaine stand as it is omitted from the list of principal drugs of psychical
interest.  This omission may have been intentional, but could alternatively be attributed to a copyist's error.$FL
$IX$LP$AF040$SZ13$PL.12$CC
$ZL$FL
$MS0107$STc1$SZ14III.$ENT$PH$PHhe$ENA$PHb$PHuse$ENof$END$PHr$PH$PHu$PHgs$SZ13$FL
$MS0600$AF009$RC0030$STa3A.$EN$PH$PH$PH$PH$PH$PH$PH$RCWhy people resort to drugs.$US$FL
$TB$LL0304$STa3$SZ13$RX$IL0108$TB$LL1602$STa3$SZ13$RX$IR0104$TB$LL0108$STa3$SZ13$RX$TB$LL1410$STa3$SZ13$RX$ZL$TE
$TB$EN1.$TBPersonal idiosyncrasy.$TB$EN2.$TBThe search for new sensations.$US$TE
$TB$EN3.$TBFailure to f$UM$UMit environment.$TB$EN4.$TBIgnorance.$US$TE
$TB$EN5.$TBEconomy.$TB$EN6.$TBHypocrisy.  (Where Public Opinion
condemns pleasure, those who fear it
resort to secret vices.)$US$TE
$TB$BP$EN7.$TBAmbition to obtain praeterhuman
power or knowledge.$TB$BR$EN8.$TBThe stress of modern life.$US$TE
$FL
$TB$EN9.$TBExcess of imagination.$TB10.$TBExcess of sensitiveness.$US$TE
$TB11.$TBEnnui.$TB12.$TBPain.$US$TE
$TB13.$TBMoral weakness.$TB14.$TBVice.$US$TE
$PP$PP$RC0030B.$EN$FS$UM$UM$RCCommoner results of abuse.$US$FL
$LU$IL0030$ST4$BPAlcohol:$ST3$ENwell known. $US$FL
$ST4Hashish:$ST3$ENinsanity.$US$FL
$ST4Chloroform:$ST3$ENfew cases known.$US$FL
$ST4Opium (smoking$PH$PH$PH):$ST3$ENbad results rare.$US$FL
$FL
$ST4Morp$UM$UMhine:$ST3$ENnervous collapse, madness,$FL
$EMinsomnia, digestive trouble.$US$FL
$IX$LP$IL1906$BR$ST4Ether:$ST3$ENthe alcohol plus paralysis.$US$FL
$ST4Anhalonium Lewinii:$ST3$ENinsanity.$US$FL
$ST4Cocaine:$ST3$ENnervous collapse, insanity.$US$FL
$ST4Laudanum:$ST3$ENsee De Quincey, Coleridge,
$EMand Wilkie Collins.*$US$FL
$ST4Heroin:$ST3$ENlike Morphine, with great$FL
$EMdullness and depression.$US$FL
$PP$PP$IX$RC0030C.$EN$FS$UM$RCConditions which lead from use to abuse.$US$FL
$PP$PP$RC0030D.$EN$PH$PH$PH$PH$PH$RCDif$UM$UMf$UM$UMiculties in the way of stopping.  Nature of the temptation to go on.$US$FL
$EMIn the case of Alcohol and Ether I f$UM$UMind no inclination to do so, I take either quite
casually, but instinctively avoid frequent repetition.$US$FL
$EMWith Hashish and Anhalonium, I have a powerful repulsion and can only force myself
to take them by a stern sense of duty.$US$FL
$EMWith Opium smoking, I indulge very mildly when the company is attractive; I have
tried long and vainly to acquire the habit.$US$FL
$EMWith Morphine, I dislike the effect subconsciously; no temptation to repeat.$US$FL
$EMWith Cocaine, the f$UM$UMirst few sniffs produce an impatient uneasiness; I am almost
irresistably driven to go on to my physiological limit for that time; but privation causes
neither suffering nor regret.$US$FL
$EMWith Heroin over-indulgence always causes vomiting.  I have succeeded in acquiring
enough of a habit to make it hard to break off.  The symptoms are severe; but now that I
know how to employ palliatives, I can break away sharply and survive the craving with
four days moderate discomfort at most. Suppression causes fear, which induces
resumption; and f$UM$UMills the mind with specious arguments in favour of taking `one last dose'.$US$FL
$FL
$MS0200$IX$STc1$SZ14IV$UM$UM$UM$UM.$ENC$PH$PHom$PHm$UMerc$PHi$PHa$PHl$ENA$PHspect$PHs$SZ13$FL
$MS0600$AF009$STa3$RC0030A.$EN$PH$PH$PH$PH$PH$PH$PH$RCEffects of repressive legislation. Enormous prof$UM$UMits to$US$FL
$TB$EN1.$TBPedlars and smugglers.$TB$EN2.$TBPolicemen.$US$TE
$TB$EN3.$TBBlackmailers.$TB$EN4.$TBQuack doctors.$US$TE
$TB$EN5.$TBSanitarium sharks.$TB$EN6.$TBSecret nostrum vendors.$US$TE
$TB$EN7.$TBSensational journalists.$TB$EN8.$TBSpies and of$UM$UMf$UM$UMicials.$US$TE
These would vanish if prohibition became effective or the laws were abolished.$US$FL
$PP$PP$IX$LP$RC0030B.$EN$PH$PH$PH$PH$PH$PH$PH$PH$PH$PH$RCCost to nation.$US$FL
$TB$EN1.$TB$LL3208$IXLoss of `victims'$PH$PH$PH$PH$PH' economic value.$US$TE
$TB$EN2.$TBMaintenance of machinery of prohibition; inspectors, spies etc., support of$FJ
convicts.$TE
$FL
$SZ10$PL.09$ST1*$ST3$FSLaudanum is a tincture of opium.  See Thomas De Quincey, $ST4Confessions of an Opium Eater$ST3, (London: Cresset Press,
1950), Samuel Taylor Coleridge, ``Kubla Khan'', in $ST4The Complete Poetical Works of Samuel Taylor Coleridge$ST3, ed. E.H.
Coleridge, vol. I, pp.$FS295-298, (London: Oxford University Press, 1912), and Wilkie Collins, $ST4The Moonstone$ST3,
(London: Collins, 1925).$FL
$SZ13$PL.12$AF040$FL
$TB$EN3.$TBLoss of dignity, by making physicians and pharmacists subject to police degrades
those professions, keeps away the best class of men from them, and so destroys the
nation's health.$US$TE
$PP$PP$RC0030C.$EN$PH$PH$PH$PH$PH$PH$PH$PH$PH$PH$PH$RCCheapness of drugs tends to drive out alcohol.  Most drugs can be made synthetically from
`harmless' ingredients.$US$FL
$CC
$MS0206$STc1$SZ14V$UM$UM$UM$UM.$ENT$PH$PHhe$ENT$UM$UM$UM$UM$UMre$PHa$UM$PHm$UM$UMe$PHnt$ENof$END$PHr$PH$PHu$PHg$ENHabit$PHs$SZ13$FL
$MS0600$AF009$STa3$RC0030A.$EN$PH$PH$PH$PH$PH$PH$PH$RCSome drugs, $ST4e.g.$ST3 Opium, produce a physical craving due to the chronic poisoning of the
tissues.  Suppression may therefore be fatal. The symptoms of suppression may be so severe
that even strong willed people need assistance in stopping.  Others, $ST4e.g.$ST3 Cocaine, present
little physical obstacle to suppression; the pull is mainly moral.$US$FL
$PP$PP$RC0030B.$EN$FS$UM$UM$RCEach patient needs special treatment. This depends on$US$FL
$TB$EN1.$TB$LL1602$IR0104The original cause of the habit.$TB$EN2.$TBHis constitution.$US$TE
$TB$EN3.$TBHis environment.$TB$EN4.$TBHis prospects for the future.$US$TE
$PP$PP$RC0030C.$EN$UM$FS$RCVarious theories of cure; the main objection to each.$US$FL
$PP$PP$RC0030D.$EN$PH$PH$PH$PH$PH$RCMy own theory and practice.$US$FL
$EMThe Law of Thelema is the cure.  Each patient must be analysed until he discovers for
himself the true purpose for which he came into the world.  He will then resolve f$UM$UMirmly to
stop drugs as hindrances to his doing his will.  He is assisted by palliatives when any
physical symptoms tend to overcome his resolution.$US$FL
$PP$PP$IX$RC0030E.$EN$FS$UM$UM$UM$UM$RCPalliatives useful in various crises.$US$FL
$CC
$MS0110$STc1$SZ14VI.$ENT$PH$PHhe$ENMa$PHster$PH$PHy$ENof$END$PHr$PH$PHu$PHgs$SZ13$FL
$MS0600$AF009$STa3$RC0030A.$EN$PH$PH$PH$PH$PH$PH$PH$RCMan must be trained to use drugs with impunity.$US$FL
$PP$PP$RC0030B.$EN$FS$UM$UM$RCExperiments must be made to discover how the undoubted physical and moral assistance
of drugs may be turned to the best advantage.$US$FL
$PP$PP$RC0030C.$EN$UM$FS$RCResults of my own researches in this direction.$US$FL
$LP$IX$LL0410$ST4Alcohol.$ZL$FR
$LL3600$IL0504$ST3T$UM$UM$UMoo general in its action to be useful.$US$FL
$IX$LL0410$ST4Ether.$ZL$FR
$LL3600$IL0504$ST3Invaluable for mental analysis; also to discover one's own f$UM$UMinal judgment on
any matter.  Gives the power to appreciate the elements of which sensation is
made up.  $ST4Example:$ST3 Feeling one's f$UM$UMinger move in detail.$US$FL
$IX$LL0410$ST4Hashish.$ZL$FR
$LL3600$IL0504$ST3Good for mental analysis.  Aids imagination and builds up courage.  One can
trace the genesis of ideas, solution sometimes given in a series of pictures.
$ST4Example:$ST3 How property began.$US$FL
$IX$LL0410$ST4$BPAnhalonium$FR
$MP$MPLewinii.$EN$FR
$BR$LL3600$IL0504$ST3Like Hashish.  (All three excellent for enabling one to get behind one's
superf$UM$UMicial ideas and discover the roots of one's thoughts.)$US$FL
$IX$LL0410$ST4$BPMorphine,$FR
$MP$MPOpium etc.$EN$FR
$BR$LL3600$IL0504$ST3Aids concentration.  Relieves pressure of worrying thoughts; aids creative
imagination.  $ST4Objection:$ST3$ENInjures executive ability, so that ideas are sterile.$US$FL
$IX$LL0410$ST4Cocaine.$ZL$FR
$LL3600$IL0504$ST3Prevents fatigue, enabling one to work at full pressure for an indef$UM$UMinite time.
$ST4Example:$ST3 My New Orleans method and work done at Cefalu.*$US$FL
$IX$LL0410$ST4Heroin.$ZL$FR
$LL3600$IL0504$ST3Combines the virtues of Opium and Cocaine.  Excites imagination; helps
concentration and calm; increases executive power and endurance.  $ST4Example:$ST3
$ST4[The Diary of a] Drug Fiend$ST3.$SSi$US$FL
$PP$PP$IX$RC$SX0030D.$EN$PH$PH$PH$PH$PH$RCThe Technique of Administration.  Select proper drug by experiment.  Dosage.  The
Opsonic curve.$SSo  $SXThe weather and other conditions.$FL
$FL
$SZ10$PL.09*$FSThe New Orleans Method is described as ``exciting the mind by morphine and then steadying it by cocaine'' in $ST4The
Magical Record of the Beast 666$ST3, ed. Symonds & Grant, (Montreal: 93 Publishing, 1972), p. $EN$EN$EN, which also
documents Crowley's work at Cefalu, pp.$FS83-300, $ST4passim$ST3.$FL
$PP$PP$SSi$FS$ST4$SXThe Diary of a Drug Fiend$ST3, (London: Collins, 1922).$FL
$PP$PP$SSo$FS$SXProbably a drug-tolerance curve plotting dosage, time (frequency) and the opsonic index (which indicates the levels
of opsonin, a component of blood serum that renders foreign matter, including drug molecules, susceptible to attack
by phagocytes).  As the opsonic index rose, dosage would have to rise to maintain the same degree of intoxication.$FL
$LP$MS0000$IX$AF040$FL